nicorandil

NICORANDIL

• It belongs to a novel class of agents of the management of coronary heart diseases.
• It has a dual mode of acton being a selective ATP dependent  potassium channel opener and a nitric oxide donor.

INDICATONS :

• Long term management of coronary heart disease

DOSE :

• ADULTS : 10-20 mg twice day
• CHILDREN : Not recommended.

CONTRAINDICATIONS :

• Hypersensitivity
• Patients with cardiogenic shock
• left ventricular failure with low filling pressure and in hypotension.

SPECIAL PRECAUTIONS :

• Patients on Nicorandil theraypy should not drive or operate machinery.

      IT AVOIDED IN THE PATIENTS WITH

• depleted blood volume
• low systolic blood pressure
• acute pulmonary oedema or Acutue Myocardial infarctions
• Acute left ventricular failure and low filling pressure.
• Paediatric : Not recommended.
• Pregnancy and Lactaion :Should not be used as there is no experience in humans.
• Elderly : No special problem.

SIDE EFFECTS :

• Headache.
• Cutaneous vasodilation with flushing.
• Nausea.
• Vomiting.
• Dizziness.
• Feeling of weakness.

DRUG INTERACTIONS :

                     No pharmacological or pharmacokinetic interactons have been observed with

• Beta-blockers
• Digoxin
• Rifampicin
• Cimetidine
• Frusemide

Click here & Download a Document

 I inviting the people who intrest to publish your mateirals in the website

Contact :

Email : krs986@gmail.com

Cell : 9059999716